Patch fluorometry: shedding new light on ion channels.
نویسنده
چکیده
Patch fluorometry has emerged as a new approach to the study of the structure-function relationship in membrane-embedded functional ion channels. Simultaneous fluorescent and electrical recordings are achieved from a small number of channels in a cell-free membrane patch, yielding high recording sensitivities. Further improvement of this approach should permit direct observation of the gating motion of a single-channel protein.
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عنوان ژورنال:
- Physiology
دوره 21 شماره
صفحات -
تاریخ انتشار 2006